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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM48 All Species: 10.91
Human Site: S613 Identified Species: 24
UniProt: Q9BTX1 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTX1 NP_060557.2 674 76305 S613 F K L P H A S S K P P R I S G
Chimpanzee Pan troglodytes XP_513417 776 87618 S715 F K L P H A S S K P P R T S G
Rhesus Macaque Macaca mulatta XP_001091911 530 59703 L477 G S P Q S P Q L I R R G P R L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8VCB1 673 75391 P614 L P H A S S K P P R A S G S L
Rat Rattus norvegicus Q6AXN4 673 75694 P614 L P H A S S K P P R T S G S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518195 431 47121 S376 V K V R G F L S K R A L I V Y
Chicken Gallus gallus XP_001235442 684 77153 K624 K L P H V S S K P P R S S G S
Frog Xenopus laevis Q6AX31 660 74320 S607 K P A R N P G S L L D S S C K
Zebra Danio Brachydanio rerio Q7SZC5 671 74423 S610 F K L P H A S S K P A R T V C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCG4 578 65368 V525 E L D K L S S V I G N I R I S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784037 756 85199 T702 Q Q F L Q L A T E V M D T P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86 76.4 N.A. N.A. 87 86.9 N.A. 20.4 67.8 56.8 53.5 N.A. 22.7 N.A. N.A. 28.1
Protein Similarity: 100 86.2 77.3 N.A. N.A. 92.1 92.5 N.A. 33.5 79.3 72.4 72.2 N.A. 43.4 N.A. N.A. 45.3
P-Site Identity: 100 93.3 0 N.A. N.A. 6.6 6.6 N.A. 26.6 13.3 6.6 73.3 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 93.3 0 N.A. N.A. 13.3 13.3 N.A. 33.3 20 13.3 73.3 N.A. 13.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 19 0 28 10 0 0 0 28 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 10 10 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 28 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 10 0 10 0 0 10 0 10 19 10 19 % G
% His: 0 0 19 10 28 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 19 0 0 10 19 10 0 % I
% Lys: 19 37 0 10 0 0 19 10 37 0 0 0 0 0 10 % K
% Leu: 19 19 28 10 10 10 10 10 10 10 0 10 0 0 28 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 28 19 28 0 19 0 19 28 37 19 0 10 10 0 % P
% Gln: 10 10 0 10 10 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 19 0 0 0 0 0 37 19 28 10 10 0 % R
% Ser: 0 10 0 0 28 37 46 46 0 0 0 37 19 37 28 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 10 0 28 0 0 % T
% Val: 10 0 10 0 10 0 0 10 0 10 0 0 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _